Background:Baclofen is a muscle relaxant that is used to treat muscle spasticity. Baclofen has been shown to have a low incidence of side effects including muscle pain, nausea, headache, and insomnia. However, there is an increased incidence of muscle injury and muscle spasms in patients with cerebral palsy and other muscle spasticity disorders. We have previously reported that baclofen causes a marked reduction in muscle tone, which is beneficial for patients who have muscle weakness.
Methods:We sought to examine the effect of baclofen on muscle spasticity in patients with cerebral palsy and other muscle spasticity disorders. A retrospective review of baclofen-treated patients with cerebral palsy and other muscle spasticity disorders was performed. We also assessed baclofen-treated patients with spinal cord injury, a muscle disorder that causes muscle spasms, and patients with other muscle spasticity disorders. The study protocol was approved by the Mayo Clinic Institutional Review Board.
Results:In a total of 481 patients with cerebral palsy and other muscle spasticity disorders, the average age was 51 years (median 62.3 years). Of these, 107 patients (15%) were treated with baclofen for muscle spasticity. Of these, 118 patients (15%) were treated with baclofen for spinal cord injury and 46 patients (9%) were treated with baclofen for muscle spasticity. There were no significant differences between treatment groups for age, sex, diagnosis, treatment duration, duration of spasticity, or the incidence of muscle spasticity.
Conclusions:The use of baclofen for muscle spasticity in patients with cerebral palsy and other muscle spasticity disorders is associated with a significant reduction in spasticity, although there are no significant differences between groups in muscle tone.
However, there is an increased incidence of muscle injury and muscle spasms in patients with spinal cord injury, a muscle disorder that causes muscle spasms, and patients with other muscle spasticity disorders. We have also reported that baclofen causes a marked reduction in muscle tone, which is beneficial for patients who have muscle weakness. However, there are no significant differences between groups in muscle tone.Conclusion:Our study showed that baclofen caused a marked reduction in muscle tone in patients with cerebral palsy and other muscle spasticity disorders. We believe baclofen should be used as a first-line treatment for muscle spasticity and spinal cord injury. Patients with these disorders should undergo careful screening and follow-up for muscle spasms and should be encouraged to have a regular check-up.
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Baclofen is a prescription medicine used for muscle spasms caused by certain conditions, such as multiple sclerosis, spinal cord injuries or other spinal cord diseases. Baclofen is sold under the brand name Lioresal, and it’s one of the most popular and widely used generic versions of the drug. This makes it a reliable and effective option for treating muscle spasms, spinal cord disorders, and other muscle-related conditions.
The recommended dosage of Baclofen varies depending on the individual and the severity of the muscle spasms. The most common dose of Baclofen is 50mg. However, your doctor will decide the correct dose for you depending on your age, severity, and severity of muscle spasms. This is important as your body needs more Baclofen to function properly.
Some Baclofen side effects may include:
If you experience any of these side effects, contact your doctor immediately. They can also advise on adjusting the dosage or monitoring your progress.
The side effects of Baclofen may include:
If you experience any of the above side effects, you should seek medical attention immediately.
If you’re taking Baclofen and have any medical conditions, such as a heart condition, low blood pressure, kidney or liver problems, or a stroke, you should seek medical help immediately. The following is a list of possible risks associated with Baclofen.
If you have kidney problems or are taking other medications, you may need to be monitored regularly for kidney problems.
If you have liver problems, you may need to be monitored regularly for liver problems.
If you have a neurological disorder or have any neurological symptoms, you should seek medical help immediately.
If you have Hepatitis B or Hepatitis C, you may need to be monitored regularly for hepatitis B virus (HBV) infection.
If you experience any of the above side effects, contact your doctor immediately.
The following is a list of possible side effects associated with Baclofen.
While Baclofen may be effective for some muscle spasms, it may not be safe for everyone. Here are some potential side effects of Baclofen to watch for:
If you are taking any of the above medications, you should consult your doctor before starting Baclofen. They can assess whether the Baclofen should be used together with other medications or whether you should use other medications together.
Baclofen belongs to the class of medications known asmuscle relaxants. It is used totreat certain muscle spasms caused by certain types ofneuropathic pain(such as trigeminal neuralgia, fibrosing trigeminal neuralgia, and spinal cord injury).Baclofen is also used totreat muscle spasms associated with fibromyalgia(ibid.). This medication helps reduce pain and improves your ability to enjoy sleep.
This medication may be available under multiple brand names and/or in several different forms.Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles.If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor.Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do.It can be harmful for people to take this medication if their doctor has not prescribed it.
10 mgEach white, round, biconvex, scored, film-coated, scored tablet, engraved "10" on one side and "10" on the other, contains 10 mg of baclofen.Nonmedicinal ingredients:carboxylic acid, polysorbate 60, and propylacetic acid.
20 mgEach white, round, biconvex, scored, film-coated, engraved "20" on one side and "20" on the other, contains 20 mg of baclofen.
40 mgEach white, round, biconvex, scored, film-coated, engraved "40" on one side and "40" on the other, contains 40 mg of baclofen.
The recommended adult dose is 10 mg for each of the following:
The dose should be kept as low as possible to avoid the side effects of baclofen.It is important that you continue to take this medication even if you feel better.If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.Do not take a double dose to make up for a missed one.If you are not sure what to do after missing a dose, contact your doctor or pharmacist.
Store this medication at room temperature, between 68 and 77 degrees F (20 and 25 degrees C).Injectable Baclofen Solution:10 mg of baclofen per 1 mL of solution (10 mg of baclofen per 1 mL of water).
Store at room temperature between 68 and 77 degrees F (20 and 25 degrees C) and out of the reach of children.Do not refrigerate, opened and frozen, or store this medication in the refrigerator.Injectable Baclofen Solution should be administered once or twice daily at the start of a meal or within 14 days of the next dose, whichever comes first.
If you are taking baclofen for fibromyalgia, the usual adult dose is 10 mg per day.
The following are the main differences between the two medications:
Baclofen
is a medication that is prescribed to help control muscle spasticity. It works by increasing the body’s natural production of muscle. It is also available in several other formulations, such as,,, and.
This medication is usually prescribed for the short-term relief of symptoms associated with spasticity or muscle spasticity.
It is also available as a combination medication. However, the most common use is for long-term use.
In the United States, the dosage of baclofen is based on the condition the patient is suffering from. In the United States, it is also available as a combination medication.
To get the most out of this medication, it is important to follow the dosage instructions provided by your doctor. It is usually best to take it 1 to 3 hours before or 2 hours after meals. However, if you are on a high-fat meal, you may reduce the amount of baclofen by taking it at the same time each day.
The dosage may be reduced if you have any medical conditions or are taking other medications that affect the levels of baclofen in your body. It is important to take the medication exactly as prescribed by your doctor. The dosage and the timing of the dose are determined by your doctor.
The following instructions are provided by your doctor:
If you are prescribed baclofen, it is important to take it with or without food.
This medication should not be taken with alcohol.
If you are taking the medication with or without food, it is best to take it with or after a low-fat meal.
The following should be followed:
If you have any questions about the dosage and timing of the dose, you should contact your doctor.
It is important to follow the instructions provided by your doctor carefully. However, if you are unsure about the dosage and the timing of the dose, you should contact your doctor.
INDIANAPOLIS, May 27, 2013 /PRNewswire-FirstCall via COMTEX News Network/ -- Eli Lilly and Company (NYSE: LLY) today announced that its product labeling for baclofen (baclofen 10 mg/mL) has been revised to reflect the FDA's revised labeling. The company's product labeling is based on the product labeling received from the U. S. Food and Drug Administration in 2013. The revised product labeling is for baclofen 10 mg/mL. In addition, Lilly has also announced the addition of a new product monograph and a new product monograph for baclofen 10 mg/mL.
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-- Lilly's research and development. Its research and development division is located in Indiana University School of Medicine. Lilly's research and development division has more than 700 drugs and has more than 800 active ingredient formulations. For more information on the Lilly company, please visit:
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